Miller Fisher Syndrome (MFS), also called Fisher’s syndrome, usually begins with the rapid development, over days, of 3 problems:
- weak eye muscles, with double or blurred vision, and often drooping eyelids with facial weakness;
- poor balance and coordination with sloppy or clumsy walking; and
- on physical examination, loss of deep tendon reflexes, such as the knee and ankle jerk.
MMN (Multifocal Motor Neuropathy) is a rare disorder in which focal areas of multiple motor nerves are attacked by one’s own immune system. Typically, MMN is slowly progressive, resulting in asymmetrical weakness of a patient’s limbs. Patients frequently develop weakness in their hand(s), resulting in dropping of objects or sometimes inability to turn a key in a lock.
Anti-MAG peripheral neuropathy is a very rare disease, constituting perhaps 5% of CIDP-like disorders. Anti-MAG occurs when the body’s own immune system develops antibodies against a key glycoprotein (myelin-associated glycoprotein, or MAG). MAG is essential to maintaining a healthy peripheral nervous system.